How TMU researchers are advancing the understanding and treatment of cancer

February 03, 2023

Text notes it’s World Cancer Day on February 4, 2023. A closeup of a bone marrow cell, tinted blue and appearing to have ruffles, being stimulated with cytokines, which are signalling molecules used in cell communication and look like small tablets.

Researchers across Toronto Metropolitan University are researching the prevention, detection and treatment of cancer. Above is a bone marrow cell being simulated with the signalling molecules called cytokines. Photo: National Cancer Institute.

World Cancer Day on February 4 is an annual international initiative that honours those impacted by cancer and emphasizes the importance of cancer research. Across Toronto Metropolitan University (TMU), our researchers are advancing the prevention, detection and treatment of different cancers.

Brain tumour detection

TMU and Unity Health Toronto researchers from the Institute of Biomedical Engineering, Science and Technology (iBEST) have developed highly sensitive nanosensors that can detect brain cancer biomarkers in a blood sample. The TMU team, led by professor Bo Tan, has been working with neurosurgeon and scientist Dr. Sunit Das from St. Michael’s Hospital, a site of Unity Health Toronto, on this technology.

Optimizing chemotherapy through math

Using mathematical modelling and simulations (opens in new window) , professor Kathleen Wilke is helping advance the potential of personalized chemotherapy treatment options. According to professor Wilke, tailoring doses to individuals can improve their quality of life and help address unintended side effects, such as dramatic muscle and fat tissue loss.

Better imagery for earlier diagnosis

Biomedical physics PhD candidate James Day, supervised by professor Jesse Tanguay, is investigating how to improve mammographic exam images, as they play a critical role in detecting and diagnosing breast cancer. The researchers are exploring the potential of using a state-of-the-art photon-counting detector for taking these images.

Skin cancer prevention strategies

The strategies to prevent skin cancer go beyond frequent sunscreen applications. Professor Thomas Tenkate is developing an app that will offer personalized messaging to provide workers, especially those outdoors, with tips. For example, small changes, like wearing long sleeves or seeking shade for breaks, can help minimize skin damage from the sun’s UV radiation.